HealthMarch 30, 2026

Pharmacists in emergency departments: Enhancing patient care and driving efficiency

Key Takeaways

  • Embedding pharmacists in emergency departments improves medication safety, antimicrobial stewardship, and care efficiency in high‑risk, fast‑paced clinical environments.
  • The expanding role of ED pharmacists—from trauma support to dosing and culture review—has significantly increased their presence and impact on patient outcomes.
  • Clinical surveillance technology enables pharmacists to intervene earlier, reduce treatment delays, optimize antimicrobial therapy, and support cost containment in emergency departments.
Pharmacists in emergency departments improve patient safety, streamline care, and drive better outcomes in high-stakes environments.

Improving emergency department care with pharmacist expertise

In the fast-paced, high-stakes environment of an emergency department (ED), the presence of a pharmacist can significantly improve patient safety, advance antimicrobial stewardship, and increase the efficiency of the medication process. As patient cases become more complex and healthcare costs continue to increase. Pharmacists are tasked with finding ways to improve cost containment, patient safety, and transitions of care within this demanding setting.  The surveillance of high-cost medications and real-time management of shortages are critical functions that require advanced support.

The evolving role of pharmacists in emergency departments

The involvement of clinical pharmacists in the emergency department has grown substantially over the last decade. Historically, this field of clinical practice was largely left to nursing and physician colleagues, with pharmacists having minimal interaction beyond order review. There was a time when very few U.S. hospitals had pharmacists providing services directly in their EDs. Over time, the medical community has recognized the value that pharmacists can bring to patient care experiences in emergent situations where adverse drug events are more likely to occur. The percentage of hospitals with pharmacists assigned to emergency departments for eight or more hours a day rose from 10.9% in 2011 to 46.5% in 2025, according to the ASHP.

The most common roles of ED pharmacists include serving as part of the care team to assist with trauma and resuscitation, selecting proper medications in concert with appropriate dosing recommendations, providing drug information for patients and staff, management of critically ill patients, management of boarded patients, and assisting with antimicrobial stewardship.

Strategies for pharmacist involvement in emergency departments

To address these challenges and enhance patient care, hospitals can implement tangible steps to increase and optimize the role of the pharmacist in the emergency department.

1. Support a culture of safety

EDs are high-risk environments that are more prone to errors, which can result in patient or staff harm. Pharmacists can help support a culture of safety in simple ways:

  • Share examples of adverse drug events from the Institute of Safe Medication Practices (ISMP) and/or local data during staff meetings
  • Participate in rapid response, sepsis, and/or other urgent collaborative team efforts in cohort with our nursing and physician colleagues
  • Leverage technology to identify the potential for drug optimization via solutions, such as Sentri7® Pharmacy.
  • Utilize software solutions to swiftly identify admitted patients requiring additional attention to reconcile home medications
  • Engage in policy and procedure creation surrounding clinical care pathways such as sepsis, opioid stewardship, cardiac care, and antimicrobial stewardship.

For example, a clinical pharmacist-led opioid reduction program at one large tertiary care center resulted in more than a 50% reduction in ED opiate orders and discharge prescriptions. This was achieved through targeted protocol development, clinician education, and leveraging technology to optimize dosing.

2. Educate and share learnings across teams

Pharmacy practice is constantly shifting. With continually evolving literature, it’s essential to remain on the pulse of the latest data and share it across teams. How can pharmacists interact more with the Emergency Department?

  • Participate in monthly staff education to network and share ideas.
  • Establish brief presentations before the start of a shift from simple posters or handouts created by pharmacists, interns, or students.
  • Attend educational sessions with the physicians or create brief written or verbal education tools to facilitate constructive dialogue.

The role of the clinical pharmacist in the emergency department continues to expand and evolve. Establishing strong connections across care teams is essential to meeting the needs of more complex patients and improving patient care.

3. Engage at the point of care

Pharmacists are in a unique position to begin engaging with prescribers within hours of the patient receiving a diagnosis requiring antimicrobial therapy. As medication experts, we are poised to conduct assessments and provide therapy recommendations that will serve the patient, thereby increasing the expediency of access to medications and potentially reducing cost and the length of stay. One study of nearly 200 high-risk adult patients who received a first dose of antibiotics in the ED found that subsequent antimicrobial therapy ordered by ED pharmacists resulted in a significant reduction in delays in antibiotic administration and a decreased incidence of mortality.


Technology and Collaboration in Emergency Department Pharmacy

Giruzzi and colleagues conducted a retrospective, quasi-experimental study evaluating the impact of an Antimicrobial Stewardship pharmacist culture review service within the ED. Clinicians included nearly 800 patients in the analysis and used Sentri7 as part of this assessment. Their research resulted in a five-day decrease in the median time to modify inadequate therapy and an eight-day decrease in the time to culture review. The rate of combined ED revisits and readmissions was unchanged.

With advanced clinical decision support and surveillance tools, Sentri7 Pharmacy empowers pharmacists to intervene earlier in the patient admission process, improving outcomes for both medically stable and critically ill patients in the ED. As emergency departments face increasingly complex cases and longer patient stays, Sentri7 becomes an indispensable tool. It streamlines clinical interventions, addresses medication shortages, and supports cost-containment efforts. Features like alerts for renal dosing adjustments and patient education on direct oral anticoagulants demonstrate how Sentri7 enhances efficiency and ensures optimal care. By combining pharmacists' expertise with powerful tools, Sentri7 is driving the expanded role of pharmacists in emergency medicine.

Learn About Sentri7
Stacey-McCoy
Pharmacy Clinical Program Manager

Dr. Stacey McCoy has over 20 years of experience as a clinical pharmacist. Her most recent clinical practice included more than 12 years of experience as an adult emergency medicine specialist.

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